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Dextran 40 CAS 9004-54-0

Dextran 40 CAS 9004-54-0

Dextran 40, CAS NO.9004-54-0, White powderl, according to CP,USP,BPand EP standard. Mainly used to the production of Dextran 40 injection, compound dextran injection and other dextran derivative. It can also be used as fillers and excipients in lyophilized powder preparation.

Dextran 40

Synonym: Dextran 40000; Dextran D-40

CAS NO: 9004-54-0

Molecular formula: [C6H10O5]n

Property:

White powder, odourless, tasteless. Easy soluble in hot water, insoluble in ethanol.

Application: 

It is mainly used to the production of Dextran 40 injection, compound dextran injection and other dextran derivative. It can also be used as fillers and excipients in lyophilized powder preparation.  

Specification (CP 2015):

Items

Quality

Characters

White   powder, tasteless and odourless, easily soluble in hot water, insoluble in   ethanol.

Specific   Optical Rotation

+190°   ~ +200°

Identification

Should   be positive

Chloride

≤0.25%

Nitrogen

≤0.007%

Loss   on drying

 ≤5.0%

Residue   on ignition

 ≤0.5% 

Heavy   Metals

 ≤0.0008%

Molecular-Mass   Distribution

 3200042000

 ≤120000

 ≥5000

Specification (EP 8.0):

Items

Quality

Molecular weight

35000~45000

Molecular weight distribution

M10 ≤110000

M90 ≥7000

Solubility

Very soluble in water, very slightly in alcohol, Clear   and colorless solution

Identification


Specific optical rotation

+195.0~+201.0°

Infrared absorption spectrogram

Comparing with the spectrum obtained from dextran CRS

Acidity / alkalinity

Reaction with phenolphthalein ,NaOH and HCl

Nitrogen

≤110ppm

Residual solvents


Ethanol

≤0.5%

Methanol

≤0.05%

Other

≤0.5%

Heavy metals

≤10ppm

Loss on drying

≤7.0%

Sulphated ash

≤0.3%

Bacterial endotoxins

<10 IU/g

Total viable aerobic

≤100 CFU/g

No colibacillus

Not detected

Appearance

White powder


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